GENEVA: At least 16 people have died while waiting for medical evacuation from Syria's besieged Eastern Ghouta region, the United Nations said Thursday.

Jan Egeland, head of the U.N.'s humanitarian taskforce for Syria, said a list put together several months ago of nearly 500 civilians in desperate need of evacuation was rapidly shrinking.

"That number is going down, not because we are evacuating people, but because they are dying," he told reporters in Geneva.

"We have confirmation of 16 having died on these lists since they were resubmitted in November, and it is probably higher," he said, highlighting the case of a baby who died on Dec. 14, as the latest round of Syria peace talks in Geneva ended in failure.

"I fear there will be many more. During this Christmas and holiday season, there will be more deaths unless we get evacuation going," he said.

The Eastern Ghouta region, near the Syrian capital Damascus, is one of the last strongholds of rebels fighting the forces of President Bashar Assad.

Egeland said evacuations and efforts to bring aid into the region had been blocked by a lack of authorizations from the Syrian authorities.

"This has to end," he said.

"How can we take Christmas and holidays in safety and in peace ... while the most innocent in this conflict ... are dying?"

They are dying, he said, "not because there was not relief, not because there were not people willing to go there ... but because they were part of a power play between mostly well-fed men with power and with guns."

His comments came as a new round of Syria peace talks backed by powerbrokers Russia, Iran and Turkey began Thursday in the Kazakh capital Astana.

"I hope that out of the Astana meetings in the next couple of days, we will have some kind of impulse for a change on the humanitarian said," Egeland said.

"I hope there will be a cessation of hostilities in and for Eastern Ghouta, [which] would also certainly help us in bringing in supplies, before hunger grips the whole population, and also get wounded and medical cases out," he said.

More than 340,000 people have been killed and millions have been driven from their homes since Syria's conflict erupted with anti-government protests in 2011.